SC2Spa.bm.BVMI

SC2Spa.bm.BVMI(adata1: AnnData, adata2: AnnData, GL: list, coords_name='spatial', n_neighbors=300, max_dis=1700)

Calculate bivariate Moran’s I of the genes of two ST data.

The two ST datasets share some or all ST voxels/cells

Parameters

adata1: a anndata object.
adata2: a anndata object that has the same voxels as or share part of the voxels with adata1. The obs_names of the two objects should be consistent to extract the overlapped voxels.
GL: The list of genes to be calculated. The genes should be in var_names of: adata1 and adata2
coords_name: the spatial information should be stored in adata2.obsm[coords_name]
n_neighbors: the number of max neighbors for the knn algorithm
max_dis: max distance of two neighbors

MoranI_BV

a dataframe contains the gene name information and bivariate: moran’s I values