SC2Spa.me.DEEI_sub

SC2Spa.me.DEEI_sub(ij: list, Count_excl: array, Prob_excl: array, A_S: array, A_E: array, genes: list, n_cell: int, p_coef: int)

Calculate Balanced Mutual exclusivity and Directed exclusively express index (subprocess)

Parameters

ij: indices of gene pairs
Count_excl: Count matrix of exclusive events. Prob_excl[i, j]: the probability that gene i is expressed

but gene j is not expressed
Prob_excl: Probability matrix of exclusive events. Count_excl[i, j]: number of occurrence that gene i is expressed

but gene j is not expressed
A_S: boolean matrix, True if a gene is suppressed in one cell. Shape is (cell, gene).
A_E: boolean matrix, True if a gene is expressed in one cell. Shape is (cell, gene).
genes: A list of genes
n_cell: number of cells
p_coef: penalty factor